By Nathan Kaplan
From Cyclotrons to Cytochromes: Essays in Molecular Biology and Chemistry specializes in the makes use of of the cyclotron and radioactive isotopes in molecular biology and chemistry. The ebook features a tribute to Martin Kamen, who performed an incredible function within the improvement of biochemical sciences within the usa, fairly via his examine at the cyclotron. The textual content additionally records examine on isotopes performed on the Radiation Laboratory of the college of California at Berkeley in the course of the Nineteen Thirties, in addition to the function of radioactive carbon in bacterial metabolism and experimental paintings on cytochromes.
This quantity is equipped into six sections encompassing fifty four chapters and starts with an outline of technology and expertise, after which discusses carbon-14 and its half-life. the subsequent chapters speak about the chemistry and constitution of cytochromes; the function of cytochromes and redox platforms in photosynthesis; the organic features of phosphorylation and oxidation; and protein constitution. The booklet additionally methodically explains the regulatory mechanisms and miscellaneous metabolic approaches reminiscent of the metabolism of cyclic nucleotides and comparable compounds; organic capabilities of lactate dehydrogenase; and nucleotide excision fix of broken DNA. the ultimate bankruptcy discusses the deamidation of asparagine and glutamine aspect chains whilst included into polypeptide chains, near to the function of cryptic amidase energetic websites in catalyzing the method.
This ebook is a priceless source for biochemists and molecular biologists.